Inflammation of the kidneys caused by the autoimmune disease Systemic Lupus Erythematosus (SLE) is called lupus nephritis. This complex condition prevents the kidneys from properly removing waste from the blood and regulating the amount of fluid in the body.

Symptoms of lupus nephritis could include:

• High blood pressure (hypertension)
• Exhaustion
• Increase in weight
• Foamy or frothy urine
• Swelling of the lower extremities (legs, feet and ankles)